Chromosome mapping: Radiation hybrid data and stochastic spin models
نویسندگان
چکیده
منابع مشابه
Chromosome mapping: Radiation hybrid data and stochastic spin models.
This work approaches human chromosome mapping by developing algorithms for ordering markers associated with radiation hybrid data. Motivated by recent work of Boehnke et al. [1], we formulate the ordering problem by developing stochastic spin models to search for minimum-break marker configurations. As a particular application, the methods developed are applied to 14 human chromosome-21 markers...
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ree porcine genes, AMPD1 (encoding muscle isoform of adenosine monophosphate deaminase), PKLR (encoding liver and red blood cell isozymes of pyruvate kinase) and CHRNB2 (encoding neuronal nicotinic acetylcholine receptor, beta 2 polypeptide), were assigned to the radiation hybrid map of chromosome 4 using PCR amplification on clones of the IMpRH panel. PKLR was mapped between markers SW270 and...
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A radiation hybrid (RH)-derived physical map of 25 markers on the feline X chromosome (including 19 Type I coding loci and 6 Type II microsatellite markers) was compared to homologous marker order on the human and mouse X chromosome maps. Complete conservation of synteny and marker order was observed between feline and human X chromosomes, whereas the same markers identified a minimum of seven ...
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Zinc finger genes have been shown to be involved in many different functions of the organism, such as development, differentiation (Krempler et al., 1999) and cancer (Stein et al., 1999). The human zinc finger gene ZNF151, has high homology to a murine POZ/zinc finger transcription factor gene, Zfp100, which is expressed in most tissues. Peukert et al. (1997) found that ZNF151 has a potent grow...
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ژورنال
عنوان ژورنال: Physical Review E
سال: 1995
ISSN: 1063-651X,1095-3787
DOI: 10.1103/physreve.52.895